The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 29, 2024
Filed:
Nov. 17, 2023
Escient Pharmaceuticals, Inc., San Diego, CA (US);
Marion Lanier, San Diego, CA (US);
Marcus Boehm, San Diego, CA (US);
Liming Huang, San Diego, CA (US);
Esther Martinborough, San Diego, CA (US);
Marcos Sainz, San Diego, CA (US);
Brandon Selfridge, San Diego, CA (US);
Adam Yeager, San Diego, CA (US);
ESCIENT PHARMACEUTICALS, INC., San Diego, CA (US);
Abstract
Methods are provided for modulating MRGPRX2 generally, or for treating a MRGPRX2 or a MRGPRX2 ortholog dependent condition, more specifically, by contacting the MRGPRX2 or the MRGPRX2 ortholog by administering to a subject in need thereof, respectively, an effective amount of a compound having structure (I): or a pharmaceutically acceptable salt, isomer, hydrate, solvate or isotope thereof, wherein W, Z, R, R, R, R, R, Rand Rare as defined herein. Pharmaceutical compositions containing such compounds, as well as the compounds themselves, are also provided.