The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 29, 2024

Filed:

Sep. 23, 2021
Applicant:

Tetra Bio-pharma Inc., Orleans, CA;

Inventors:

Harpreet Kaur, Brampton, CA;

Xuejun Liu, Toronto, CA;

Prabin Nepal, Toronto, CA;

Subakar Paramanantham, Scarborough, CA;

Monika Garg, Etobicoke, CA;

Zemin Li, Woodbridge, CA;

Andy Tjeng, Toronto, CA;

Moises Rodriguez, Moncton, CA;

Laura Jong, Montreal, CA;

Azam Mirzahossein, Blainville, CA;

Ofer Yifrach-Stav, Cote Saint Luc, CA;

Erin Bassett, Nepean, CA;

Randy Ringuette, Nepean, CA;

Charles Campbell, Kanata, CA;

Melanie Kelly, Fergusons Cove, CA;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 41/26 (2006.01); C07C 29/48 (2006.01); C07C 67/08 (2006.01); C07C 67/29 (2006.01); C07C 67/293 (2006.01); C07C 269/06 (2006.01);
U.S. Cl.
CPC ...
C07C 41/26 (2013.01); C07C 29/48 (2013.01); C07C 67/08 (2013.01); C07C 67/29 (2013.01); C07C 67/293 (2013.01); C07C 269/06 (2013.01); C07B 2200/07 (2013.01); C07C 2602/42 (2017.05);
Abstract

Disclosed herein are methods, processes and compositions for preparing a compound of formula 8: (8), and formula 18: (18). The methods and processes comprise performing a first allylic oxidation, a protection reaction, a second allylic oxidation, a reduction reaction, performing an acid-catalyzed coupling reaction, a methylation reaction and a deprotection reaction. Disclosed herein are methods, processes and compositions for enantioselectively preparing compounds of formulae 8 and 18. Also disclosed herein are compositions comprising compounds of formulae 8, 18 and/or intermediates and/or starting material thereof.


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