The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 29, 2024

Filed:

Mar. 05, 2020
Applicant:

Italfarmaco Spa, Milan, IT;

Inventors:

Stefano Turchetta, Rome, IT;

Maurizio Zenoni, Ferentino, IT;

Elio Ullucci, Latina, IT;

Stefania Cocciolo, Patricia, IT;

Giorgio Berardi, Ripi, IT;

Nakia Maulucci, Alatri, IT;

Assignee:

ITALFARMACO SPA, Milan, IT;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 271/28 (2006.01); B01J 20/286 (2006.01); C07C 269/06 (2006.01); C07C 269/08 (2006.01); G01N 30/02 (2006.01);
U.S. Cl.
CPC ...
C07C 271/28 (2013.01); B01J 20/286 (2013.01); C07C 269/06 (2013.01); C07C 269/08 (2013.01); G01N 2030/027 (2013.01);
Abstract

A process for obtaining {{6-[(diethylamino)methyl]naphthalen-2-yl}methyl[4-(hydroxycarbamoyl)phenyl]carbamate and/or pharmaceutically acceptable salts thereof having high purity is described. This process allows to obtain a product having an amount of any single unknown impurity equal to or less than 0.10%, as well as a product having a purity greater than 99.5%, preferably equal to or greater than 99.6%. An HPLC method for determining the purity of the product and possible impurities thereof is also described.


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