The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 29, 2024
Filed:
Dec. 15, 2022
Applicant:
Acuitas Therapeutics, Inc., Vancouver, CA;
Inventors:
Xinyao Du, Richmond, CA;
Steven M. Ansell, Vancouver, CA;
Jason Samuel Tan, Vancouver, CA;
Polina Blagojevic, Vancouver, CA;
Stephen Paul Arns, Vancouver, CA;
Julia Gatenyo, Vancouver, CA;
Assignee:
Acuitas Therapeutics, Inc., Vancouver, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 237/06 (2006.01); A61K 9/51 (2006.01); A61K 31/7105 (2006.01); C07C 237/22 (2006.01); C07D 233/64 (2006.01);
U.S. Cl.
CPC ...
C07C 237/06 (2013.01); A61K 9/5123 (2013.01); A61K 31/7105 (2013.01); C07C 237/22 (2013.01); C07D 233/64 (2013.01); C07C 2601/04 (2017.05);
Abstract
Compounds are provided having the following structure: or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R, L, L, G, Gand Gare as defined herein. Use of the compounds as a component of lipid nanoparticle formulations for delivery of a therapeutic agent, compositions comprising the compounds and methods for their use and preparation are also provided.