The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 29, 2024
Filed:
Jul. 26, 2022
10x Genomics, Inc., Pleasanton, CA (US);
Hanyoup Kim, Foster City, CA (US);
Augusto Manuel Tentori, Dublin, CA (US);
Siyuan Xing, Newark, CA (US);
Rajiv Bharadwaj, Pleasanton, CA (US);
Bill Kengli Lin, Pleasanton, CA (US);
Felice Alessio Bava, Pleasanton, CA (US);
Pratomo Putra Alimsijah, Pleasanton, CA (US);
Nabil Mikhaiel, Dublin, CA (US);
10x Genomics, Inc., Pleasanton, CA (US);
Abstract
Provided herein is a fluid delivery method for permeabilizing a biological sample. The method includes delivering the fluid to a first substrate and/or a second substrate. At least one of the first substrate and the second substrate includes a spacer. The method further includes assembling, subsequent to the delivering, a chamber comprising the first substrate, the second substrate, the biological sample, and the spacer. The spacer may be disposed between the first substrate and second substrate. The spacer may be configured to maintain the fluid within the chamber and maintain a separation distance between the first substrate and the second substrate. The spacer may be positioned to at least partially surround an area on the first substrate on which the biological sample is disposed and/or at least partially surround the array disposed on the second substrate.