The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 29, 2024

Filed:

May. 13, 2019
Applicant:

Globeimmune, Inc., Louisville, CO (US);

Inventors:

Thomas H. King, Denver, CO (US);

Zhimin Guo, Superior, CO (US);

Courtney Fleenor, Arvada, CO (US);

Assignee:

GlobeImmune, Inc., Louisville, CO (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 36/06 (2006.01); A61K 39/00 (2006.01); C12N 1/06 (2006.01);
U.S. Cl.
CPC ...
A61K 36/06 (2013.01); A61K 39/0011 (2013.01); C12N 1/063 (2013.01); A61K 2039/572 (2013.01); A61K 2039/575 (2013.01);
Abstract

Disclosed are immunogenic pharmaceutical compositions comprising yeast lysates for inducing cellular immune responses, methods of making immunogenic compositions comprising yeast lysates, methods of treatment comprising administration of said compositions, and kits comprising said yeast lysate compositions. Disclosed immunogenic compositions further comprise an antigen heterologous to the yeast, and may comprise whole yeast and immunostimulatory agents. Induced cellular immune responses comprise cytotoxic T cell activation with specificity to the antigen comprising the immunogenic composition. Various methods of formulation and administration to a patient are described herein, especially wherein the patient suffers from an infectious disease and/or cancer.


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