The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 29, 2024
Filed:
Mar. 18, 2022
Novo Nordisk Health Care Ag, Zurich, CH;
Anna Ericsson, Shrewsbury, MA (US);
Neal Green, Newton, MA (US);
Gary Gustafson, Ridgefield, CT (US);
David R. Lancia, Jr., Boston, MA (US);
Gary Marshall, Watertown, MA (US);
Lorna Mitchell, Cambridge, NZ;
David Richard, Littleton, MA (US);
Zhongguo Wang, Lexington, MA (US);
Sanjeev Forsyth, Milton, MA (US);
Patrick F. Kelly, Concord, MA (US);
Madhu Mondal, Winchester, MA (US);
Maria Ribadeneira, Cambridge, MA (US);
Patricia Schroeder, Somerville, MA (US);
Novo Nordisk Health Care AG, Zurich, CH;
Abstract
The compound (S)-1-(5-((2,3-dihydro-[1,4]dioxino[2,3-b]pyridin-7-yl)sulfonyl)-3,4,5,6-tetrahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)-3-hydroxy-2-phenylpropan-1-one, or a pharmaceutically acceptable salt thereof, is useful to increase the affinity of hemoglobin for oxygen. Methods and compositions for the treatment of a hemoglobinopathies are provided herein, including certain pharmaceutical compositions for activating PKR.