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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12123876 B1

PDFFull Text
Date of Patent:
Oct. 22, 2024

Filed:

Jan. 16, 2017

Antibody binding to heg1 and use of the antibody for detection and treatment of mesothelioma

Applicants:

Kanagawa Prefectural Hospital Organization, Yokohama, JP;

The University of Tokyo, Tokyo, JP;

Inventors:

Shoutaro Tsuji, Toyko, JP;

Taihei Kageyama, Toyko, JP;

Kota Washimi, Tokyo, JP;

Makiko Tsuji, Tokyo, JP;

Rieko Matsuura, Toyko, JP;

Mitsuyo Yoshihara, Yokohama, JP;

Kohzoh Imai, Tokyo, JP;

Assignees:

Kanagawa Prefectural Hospital Organization, Yokohama, JP;

The University of Tokyo, Tokyo, JP;

Attorneys:

Clark & Elbing LLP

Susan M. Michaud

Primary Examiner:

Michael Allen

Int. Cl.
CPC ...
G01N 33/574 (2006.01); A61K 39/395 (2006.01); A61K 49/00 (2006.01); A61K 49/16 (2006.01); A61P 35/00 (2006.01); C07K 14/705 (2006.01); C07K 16/30 (2006.01); C07K 16/46 (2006.01); C12N 15/09 (2006.01); C12N 15/62 (2006.01); G01N 33/577 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/574 (2013.01); A61K 39/395 (2013.01); A61K 49/00 (2013.01); A61K 49/0058 (2013.01); A61K 49/16 (2013.01); A61P 35/00 (2018.01); C07K 14/705 (2013.01); C07K 16/30 (2013.01); C07K 16/3092 (2013.01); C07K 16/46 (2013.01); C12N 15/09 (2013.01); C12N 15/62 (2013.01); G01N 33/57423 (2013.01); G01N 33/68 (2013.01);
Abstract

The present invention provides an antibody for detecting mesothelioma and an antibody having high specificity to mesothelioma and high sensitivity thereto. The present invention also provides a method of diagnosis of mesothelioma by using the antibody, a reagent containing the antibody for use in diagnosis of mesothelioma, and a kit comprising the antibody for use in diagnosis of mesothelioma. Further, the present invention provides a marker for use in diagnosis of mesothelioma. Furthermore, the present invention provides a pharmaceutical composition containing the antibody according to the present invention or an antigen-binding fragment thereof for use in treatment of mesothelioma. An antibody that binds to a glycosylated HEG1 protein obtained from mesothelioma.

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Tsuji, Shoutaro. (2024). Antibody binding to heg1 and use of the antibody for detection and treatment of mesothelioma (U.S. Patent No. 12123876). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12123876

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