The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 22, 2024

Filed:

Dec. 03, 2019
Applicant:

3m Innovative Properties Company, St. Paul, MN (US);

Inventors:

Tonya D. Bonilla, Woodbury, MN (US);

Stephen B. Roscoe, Woodbury, MN (US);

George W. Griesgraber, Eagan, MN (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 17/075 (2006.01); A61L 2/28 (2006.01); C12Q 1/22 (2006.01); G01N 21/64 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/22 (2013.01); A61L 2/28 (2013.01); C07H 17/075 (2013.01); G01N 21/6428 (2013.01); G01N 2021/6439 (2013.01);
Abstract

A self-contained biological sterilization indicator comprises: a housing; bacterial spores comprising, and/or capable of producing, an enzyme capable of catalyzing cleavage of an enzyme substrate; and a frangible container containing a composition, wherein the composition comprises the enzyme substrate, wherein if the frangible container is broken the composition will contact the bacterial spores to form a mixture having an initial pH in the range from 6.0 to 9.0. The enzyme substrate comprises a fluorinated 4'-alkylumbelliferyl α-D-glucopyranoside represented by the structural formula (I) wherein one of Rand Ris F and the other is H, and Ris an alkyl group having from 1 to 12 carbon atoms. A biological sterilization indicator comprising a kit containing isolated components comprising (i) bacterial spores comprising, and/or capable of producing, an enzyme capable of catalyzing cleavage of the enzyme substrate and a method of assessing efficacy of a sterilization process are also disclosed.


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