The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 22, 2024

Filed:

Dec. 20, 2022
Applicant:

Voyager Therapeutics, Inc., Cambridge, MA (US);

Inventors:

Dinah Wen-Yee Sah, Hopkinton, MA (US);

Jinzhao Hou, Lexington, MA (US);

Mathieu E. Nonnenmacher, Cambridge, MA (US);

Pengcheng Zhou, Lexington, MA (US);

Markus Hossbach, Kulmbach, DE;

Jochen Deckert, Bayreuth, DE;

Assignee:

Voyager Therapeutics, Inc., Lexington, MA (US);

Attorneys:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C12N 15/1137 (2013.01); C12Y 115/01001 (2013.01); C12N 2310/14 (2013.01); C12N 2330/51 (2013.01); C12N 2750/14143 (2013.01);
Abstract

The present invention relates to small interfering RNA (siRNA) molecules against the SOD1 gene, adeno-associated viral (AAV) vectors encoding siRNA molecules and methods for treating amyotrophic lateral sclerosis (ALS) using the siRNA molecules and AAV vectors.


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