The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 22, 2024
Filed:
Mar. 14, 2023
Applicant:
Lamkap Bio Gamma Ag, Pfaeffikon, CH;
Inventors:
Assignee:
LamKap Bio gamma AG, Pfaeffikon Sz, CH;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/46 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/468 (2013.01); A61P 35/00 (2018.01); C07K 2317/31 (2013.01); C07K 2317/565 (2013.01); C07K 2317/71 (2013.01);
Abstract
The present invention relates to GPC3×CD3 bispecific antibodies, GPC3×CD28 bispecific antibodies and the combination of two, agonistic and fully human KA-bodies with one targeting GPC3×CD3 and the other targeting GPC3×CD28, and both not competing for the binding to GPC3. The present invention also relates to the use of the bispecific antibodies for the treatment of GPC3 positive malignancies.