The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 22, 2024
Filed:
Apr. 05, 2019
Applicant:
Northwestern University, Evanston, IL (US);
Inventors:
Samuel I. Stupp, Chicago, IL (US);
Alexandra N. Kolberg, Chicago, IL (US);
Zaida Alvarez, Chicago, IL (US);
Assignee:
Northwestern University, Evanston, IL (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/475 (2006.01); C07K 7/64 (2006.01);
U.S. Cl.
CPC ...
C07K 14/475 (2013.01); C07K 7/64 (2013.01);
Abstract
Provided herein are peptide amphiphiles (PAs) and supramolecular PA nanostructures that mimic brain derived neurotrophic factor (BDNF), a growth factor that induces neuronal survival, maturation, and increased electrical activity. In particular, injectable biomaterials comprising BDNF mimetic PAs are provided, as well as methods of using BDNF mimetic PAs for the treatment or prevention of neurological injuries, diseases, and disorders.