The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 22, 2024

Filed:

Sep. 04, 2019
Applicants:

Oxford University Innovation Limited, Oxford, GB;

Freie Universität Berlin, Berlin, DE;

Inventors:

Carol V. Robinson, Oxford, GB;

Idlir Liko, Oxford, GB;

Hsin-Yung Yen, Oxford, GB;

Kevin Pagel, Berlin, DE;

Rainer Haag, Berlin, DE;

Svenja Christina Ehrmann, Berlin, DE;

Leonhard Hagen Urner, Berlin, DE;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 1/14 (2006.01); G01N 33/68 (2006.01); H01J 49/00 (2006.01); H01J 49/16 (2006.01);
U.S. Cl.
CPC ...
C07K 1/145 (2013.01); G01N 33/6848 (2013.01); H01J 49/0031 (2013.01); H01J 49/165 (2013.01);
Abstract

A method of detecting a protein by mass spectrometry comprises: providing a solution comprising a dendritic detergent and a protein; providing a mass spectrometer comprising a nanoelectrospray ionisation source, a mass analyser and a detector; vaporising the solution using the nanoelectrospray ionisation source; ionising the protein; resolving the ionised protein using the mass analyser; and detecting the resolved protein using the detector. A method of extracting a membrane protein from its native membrane comprises: providing a membrane protein in its native membrane; contacting the membrane protein with a dendritic detergent. Dendritic detergents for use in the methods are also provided.


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