The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 22, 2024

Filed:

Nov. 23, 2018
Applicant:

Oxford Nanopore Technologies Plc, Oxford, GB;

Inventor:

David Waterman, Oxford, GB;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); G01N 33/487 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502715 (2013.01); B01L 3/50273 (2013.01); B01L 3/502746 (2013.01); G01N 33/48721 (2013.01); B01L 2200/0689 (2013.01); B01L 2200/142 (2013.01); B01L 2300/043 (2013.01); B01L 2300/047 (2013.01); B01L 2300/0636 (2013.01); B01L 2300/0816 (2013.01); B01L 2400/0406 (2013.01);
Abstract

A microfluidic device for analysing a test liquid comprises: a sensor (), such as a membrane provided with nanopores, provided in a sensing chamber (); a sensing chamber inlet channel () and a sensing chamber outlet channel (), each connecting to the sensing chamber for respectively passing liquid into and out of the sensing chamber, and a reservoir () forming a sample input port to the microfluidic device, the reservoir being in fluid communication with the sensing chamber inlet channel (); a liquid collection channel (); a barrier () between an end of the sensing chamber outlet channel () and the liquid collection channel (); a first seal (), covering the sample input port: a second seal (), covering the end of the sensing chamber outlet channel (), thereby preventing liquid from flowing from the sensing chamber (), over the barrier (), into the liquid collection channel (); wherein the microfluidic device is filled with a liquid from the first seal () at the sample input port to the second seal (), such that the sensor () is covered by liquid and unexposed to a gas or gas/liquid interface; and wherein the first and second seals () are removable to cause the liquid to flow between the reservoir and the end of the sensing chamber outlet and over the barrier.


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