The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 22, 2024
Filed:
Dec. 02, 2019
Cytosorbents Corporation, Monmouth Junction, NJ (US);
Tamaz Guliashvili, Monmouth Junction, NJ (US);
Maryann Gruda, Monmouth Junction, NJ (US);
Thomas Golobish, Monmouth Junction, NJ (US);
David James, Monmouth Junction, NJ (US);
Karl-Gustav Ruggeberg, Monmouth Junction, NJ (US);
Pamela O'Sullivan, Monmouth Junction, NJ (US);
Sarah Patterson, Monmouth Junction, NJ (US);
CytoSorbents, Inc., Princeton, NJ (US);
Abstract
The invention concerns polymeric media based on modified natural polysaccharides for removing one or both of Anti-A Antibodies and Anti-B Antibodies from human blood or plasma, the media comprising one or both of (i) a polymeric solid support with a blood group A Antigen ligand attached to the solid support at a ligand loading between 1-5 mg/mL of solid support, and wherein the media is stable under physiological pH conditions, and (ii) a polymeric solid support with a blood group B Antigen ligand attached to the solid support at a ligand loading between 1-5 mg/mL of solid support, and wherein the media is stable under physiological pH conditions.