The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 22, 2024

Filed:

Sep. 27, 2022
Applicants:

Unm Rainforest Innovations, Albuquerque, NM (US);

The Johns Hopkins University, Baltimore, MD (US);

Vaxine Pty Ltd., Bedford Park, AU;

Inventors:

Bryce C. Chackerian, Albuquerque, NM (US);

Fidel P. Zavala, Baltimore, MD (US);

David S. Peabody, Albuquerque, NM (US);

Nikolai Petrovsky, Adelaide, AU;

Lucie Jelinkova, Albuquerque, NM (US);

Assignees:

UNM RAINFOREST INNOVATIONS, Albuquerque, NM (US);

THE JOHNS HOPKINS UNIVERSITY, Baltimore, MA (US);

VAXINE PTY LTD., Bedford Park, AU;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/002 (2006.01); A61K 39/00 (2006.01); A61K 39/015 (2006.01); A61P 33/06 (2006.01); C12N 15/63 (2006.01);
U.S. Cl.
CPC ...
A61K 39/015 (2013.01); A61P 33/06 (2018.01); C12N 15/63 (2013.01); A61K 2039/5258 (2013.01); A61K 2039/55561 (2013.01);
Abstract

An immunogen useful for treating malaria generally includes an immunogenic carrier and an antigenic malaria circumsporozoite protein (CSP) peptide that includes the peptide NANPNVDPNANPNVD (SEQ ID NO:2) linked to the immunogenic carrier. The immunogen may be administered to a subject having or at risk of having malaria. Alternatively, the immunogen may be administered to an individual having or at risk of havingblood stage parasitemia. In some cases, the immunogen can be administered in combination with another therapeutic agent for treating malaria ofblood stage parasitemia.


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