The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 22, 2024

Filed:

Jan. 30, 2020
Applicant:

Horizon Therapeutics Usa, Inc., Deerfield, IL (US);

Inventors:

Jeffrey D. Kent, Deerfield, IL (US);

Brian Lamoreaux, Lake Forest, IL (US);

Assignee:

Horizon Therapeutics USA, Inc., Deerfield, IL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/44 (2006.01); A61K 9/00 (2006.01); A61K 31/52 (2006.01); A61P 19/06 (2006.01);
U.S. Cl.
CPC ...
A61K 38/44 (2013.01); A61K 9/0053 (2013.01); A61K 31/52 (2013.01); A61P 19/06 (2018.01);
Abstract

The disclosure provides methods of treating gout in patients comprising administering a PEGylated uricase. Also provided are methods of treating gout in patients comprising co-administering a PEGylated uricase and azathioprine immunosuppressive therapy. Also provided are methods of reducing intolerance or enhancing immuno-tolerance to a PEGylated uricase and prolonging the urate lowering effect comprising co-administration of the PEGylated uricase and azathioprine immunosuppressive therapy.


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