The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 22, 2024

Filed:

Sep. 13, 2019
Applicants:

Mayo Foundation for Medical Education and Research, Rochester, MN (US);

Duke University, Durham, NC (US);

Laura Evgin, Rochester, MN (US);

Richard G. Vile, Rochester, MN (US);

Luis Sanchez-perez, Apex, NC (US);

Inventors:

Laura Evgin, Rochester, MN (US);

Richard G. Vile, Rochester, MN (US);

Luis Sanchez-Perez, Apex, NC (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/768 (2015.01); A61K 35/17 (2015.01); C07K 14/705 (2006.01); C07K 14/71 (2006.01); C07K 14/715 (2006.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
A61K 35/768 (2013.01); A61K 35/17 (2013.01); C07K 14/70503 (2013.01); C07K 14/71 (2013.01); C07K 14/7156 (2013.01); C12N 15/86 (2013.01); C12N 2740/15043 (2013.01); C12N 2760/20232 (2013.01);
Abstract

This document relates to methods and materials involved in treating cancer. For example, methods and materials for using one or more oncolytic viruses (OVs) in combination with an adoptive cell therapy (e.g., a chimeric antigen receptor T cell therapy) to alter one or more functions of a T cell and/or to enhance T cell expansion to treat cancer in a mammal (e.g., a human) are provided.


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