The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 22, 2024
Filed:
Sep. 10, 2016
Applicant:
Biosceptre (Aust) Pty Ltd, North Ryde, AU;
Inventors:
Justin Taylor Coombs, Wattle Park, AU;
Simon Charles Barry, Longwood, AU;
Timothy John Sadlon, Maylands, AU;
Assignee:
BIOSCEPTRE (AUST) PTY LTD, North Ryde, AU;
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 35/17 (2015.01); C07K 14/705 (2006.01); C07K 14/715 (2006.01); C07K 14/725 (2006.01); C07K 14/735 (2006.01); C07K 16/28 (2006.01); C12N 5/0786 (2010.01); C07K 19/00 (2006.01);
U.S. Cl.
CPC ...
A61K 35/17 (2013.01); C07K 14/7051 (2013.01); C07K 14/70521 (2013.01); C07K 14/70535 (2013.01); C07K 14/70578 (2013.01); C07K 14/715 (2013.01); C07K 16/28 (2013.01); C12N 5/0645 (2013.01); C07K 19/00 (2013.01); C07K 2317/622 (2013.01); C07K 2319/02 (2013.01); C07K 2319/03 (2013.01); C07K 2319/30 (2013.01); C07K 2319/33 (2013.01); C07K 2319/60 (2013.01);
Abstract
The present invention relates to chimeric antigen receptors (CARs) directed to cells expressing a dysfunctional or non-functional P2X purinoceptor 7 receptor. Further provided are methods of targeting neoplastic cells and tumours expressing a dysfunctional or non-functional P2X purinoceptor 7 receptor and methods of treating and preventing cancer is a subject.