The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 22, 2024

Filed:

Apr. 29, 2021
Applicant:

Meharry Medical College, Nashville, TN (US);

Inventor:

Donald J. Alcendor, Hermitage, TN (US);

Assignee:

Meharry Medical College, Nashville, TN (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/7125 (2006.01); A61K 47/64 (2017.01); A61P 31/14 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7125 (2013.01); A61K 47/641 (2017.08); A61P 31/14 (2018.01);
Abstract

An antiviral agent is provided, having a phosphorodiamidate morpholino oligomer with an antisense sequence to a portion of a genome of a strain of a coronavirus. The coronavirus may be SARS-CoV-2 or another βCoV. The antiviral agent finds many uses, such as in a pharmaceutical composition, a method of treating coronavirus-mediated disease, a method of preventing coronavirus-mediated disease, a method of reducing or preventing the replication of coronavirus in a host cell, a method of controlling the spread of coronavirus in donated tissue, a treated tissue sample, and in the manufacture of a medicament for the treatment or prevention or coronavirus-mediated disease.


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