The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 22, 2024
Filed:
Nov. 16, 2023
Applicant:
Gilead Sciences, Inc., Foster City, CA (US);
Inventors:
Jinfa Du, Redwood City, CA (US);
Dhanapalan Nagarathnam, Bethany, CT (US);
Michael Joseph Sofia, Doylestown, PA (US);
Peiyuan Wang, San Mateo, CA (US);
Assignee:
Gilead Sciences, Inc., Foster City, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/7072 (2006.01); A61K 31/706 (2006.01); A61K 31/7064 (2006.01); A61K 31/7076 (2006.01); A61K 45/06 (2006.01); C07D 417/14 (2006.01); C07H 17/02 (2006.01); C07H 19/04 (2006.01); C07H 19/06 (2006.01); C07H 19/10 (2006.01); C07H 19/20 (2006.01); A61K 31/7068 (2006.01); C07H 19/073 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7072 (2013.01); A61K 31/706 (2013.01); A61K 31/7064 (2013.01); A61K 31/7076 (2013.01); A61K 45/06 (2013.01); C07D 417/14 (2013.01); C07H 17/02 (2013.01); C07H 19/04 (2013.01); C07H 19/06 (2013.01); C07H 19/10 (2013.01); C07H 19/20 (2013.01); A61K 31/7068 (2013.01); C07H 19/073 (2013.01); Y02A 50/30 (2018.01);
Abstract
Disclosed herein are phosphoramidate prodrugs of nucleoside derivatives for the treatment of viral infections in mammals, which is a compound, its stereoisomer, salt (acid or basic addition salt), hydrate, solvate, or crystalline form thereof, represented by the following structure: Also disclosed are methods of treatment, uses, and processes for preparing each of which utilize the compound represented by formula I.