The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 22, 2024

Filed:

Nov. 09, 2023
Applicant:

Revolution Medicines, Inc., Redwood City, CA (US);

Inventors:

Bojena Bitman, Redwood City, CA (US);

W. Clay Gustafson, Redwood City, CA (US);

Ed Lorenzana, Redwood City, CA (US);

Justin G. Meyerowitz, Redwood City, CA (US);

Yu Chi Yang, Redwood City, CA (US);

Mallika Singh, Redwood City, CA (US);

Zhengping Wang, Redwood City, CA (US);

Zhican Wang, Redwood City, CA (US);

Assignee:

REVOLUTION MEDICINES, INC., Redwood City, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); A61K 9/00 (2006.01); A61K 31/436 (2006.01); A61K 31/4433 (2006.01); A61P 29/00 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/519 (2013.01); A61K 9/0019 (2013.01); A61K 31/436 (2013.01); A61K 31/4433 (2013.01); A61P 29/00 (2018.01); A61P 35/00 (2018.01);
Abstract

The present disclosure relates to methods for the treatment of diseases or disorders (e.g., cancer) with mTOR inhibitors. Specifically, the disclosure relates to methods of treating a subject having a cancer by administering a particular dosage of an mTOR inhibitor. In some embodiments this disclosure includes methods for delaying, preventing, or treating acquired resistance to RAS inhibitors using a dosage of an mTOR inhibitor. In some embodiments, this disclosure relates to methods of treating or preventing adverse events associated with administration of an mTOR inhibitor using tacrolimus.


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