The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 22, 2024
Filed:
Nov. 27, 2020
Applicant:
Inxmed (Nanjing) Co., Ltd., Nanjing, CN;
Inventors:
Zaiqi Wang, Shanghai, CN;
Jiangwei Zhang, Shanghai, CN;
Jun Jiang, Shanghai, CN;
Baoyuan Zhang, Shanghai, CN;
Assignee:
INXMED (NANJING) CO., LTD., Nanjing, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61P 35/00 (2006.01); A61K 31/513 (2006.01); A61K 31/519 (2006.01);
U.S. Cl.
CPC ...
A61K 31/513 (2013.01); A61K 31/519 (2013.01); A61P 35/00 (2018.01);
Abstract
The present invention relates to a method for treating a tumor with a KRAS mutation. In the method, a compound 2-fluoro-5-methoxy-4-[(4-(2-methyl-3-oxo-2,3-dihydro-1H-isoindole-4-oxy)-5-trifluoromethyl-pyrimidine-2-yl)amino]-N-(1-methyl-piperidine-4-yl)benzamide or a pharmaceutically acceptable salt thereof is used, which can be administered alone or in combination with a KRAS inhibitor and/or an MEK inhibitor.