The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 22, 2024

Filed:

Mar. 07, 2018
Applicant:

Actelion Pharmaceuticals Ltd, Allschwil, CH;

Inventors:

Klaus Hellerbrand, Martinsried, DE;

Alexandra Schlicker-Spain, Allschwil, CH;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4965 (2006.01); A61K 9/00 (2006.01); A61K 9/19 (2006.01); A61K 47/10 (2017.01); A61K 47/26 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4965 (2013.01); A61K 9/0019 (2013.01); A61K 9/19 (2013.01); A61K 47/10 (2013.01); A61K 47/26 (2013.01);
Abstract

The invention relates to aqueous pharmaceutical compositions comprising the compound 2-{4-[N-(5,6-diphenylpyrazin-2-yl)-N-isopropylamino]butyloxy}-N-(methylsulfonyl) acetamide; glycine; polysorbate 20; and an aqueous phosphate buffer, wherein the relative amounts are as described in the description, wherein the pH of said pharmaceutical composition is between about 7 and 8; to lyophilized pharmaceutical compositions prepared from said aqueous compositions, and to reconstituted aqueous compositions thereof which are suitable for i.v. administration. The invention further relates to processes for the preparation of said compositions, and to their use for the treatment of diseases and disorders which are related to IP receptor.


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