The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 15, 2024

Filed:

Dec. 22, 2021
Applicant:

Trizell Ltd., West Drayton, GB;

Inventors:

Piia Kristiina Valonen, Kuopio, FI;

Hanna P. Lesch, Kuopio, FI;

Eva Kristiina Rasanen, Hiltulanlahti, FI;

Tarja Hannele Tuunanen, Kuopio, FI;

Minna Kristiina Karhinen, Kuopio, FI;

Seppo Ylä-Herttuala, Kuopio, FI;

Assignee:

Trizell Ltd., West Drayton, GB;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12M 1/00 (2006.01); C07K 14/005 (2006.01); C12M 1/02 (2006.01); C12M 1/12 (2006.01); C12M 1/34 (2006.01); C12N 15/86 (2006.01); C12P 21/02 (2006.01);
U.S. Cl.
CPC ...
C12M 29/18 (2013.01); C07K 14/005 (2013.01); C12M 1/02 (2013.01); C12M 25/18 (2013.01); C12M 29/10 (2013.01); C12M 41/26 (2013.01); C12M 41/46 (2013.01); C12N 15/86 (2013.01); C12P 21/02 (2013.01); C12N 2740/15051 (2013.01);
Abstract

We have modified a commercially-available adherent cell culture bioreactor in several ways to increase productivity of cultured cells, while decreasing contamination risk. We found that modifying a commercially-available adherent cell culture bioreactor to provide for slower cell culture medium flow unexpectedly and dramatically increases the productivity of the cultured adherent cells. We also developed a new sampling manifold configuration and new way of taking samples, to reduce contamination risk.


Find Patent Forward Citations

Loading…