The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 15, 2024

Filed:

Oct. 23, 2023
Applicant:

Corning Incorporated, Corning, NY (US);

Inventors:

Ann MeeJin Ferrie, Salem, NH (US);

Vasiliy Nikolaevich Goral, Painted Post, NY (US);

Assignee:

CORNING INCORPORATED, Corning, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12M 1/12 (2006.01); C12M 1/00 (2006.01); C12M 3/00 (2006.01);
U.S. Cl.
CPC ...
C12M 25/02 (2013.01); C12M 23/02 (2013.01); C12M 23/20 (2013.01); C12M 23/44 (2013.01); C12M 25/14 (2013.01); C12M 29/10 (2013.01); C12M 29/26 (2013.01);
Abstract

A fixed-bed bioreactor system is provided that includes a vessel with a media inlet, a media outlet, and an interior cavity disposed between and in fluid communication with the media inlet and media outlet. The vessel further includes a cell culture substrate disposed in the interior cavity between the media inlet and the media outlet in a packed-bed configuration, the cell culture substrate including a plurality of porous disks in a stacked arrangement. The interior cavity includes a cell culture section and a spacer section, the cell culture substrate defining the cell culture section and the spacer section being disposed between the cell culture section and the media outlet, and each of the plurality of porous disks has a surface configured to culture cells thereon.


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