The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 15, 2024
Filed:
Sep. 25, 2019
Applicant:
Academia Sinica, Taipei, TW;
Inventors:
Shie-Liang Hsieh, Taipei, TW;
Pei-Shan Sung, Taipei, TW;
Ming-Ting Huang, Taipei, TW;
An-Suei Yang, Emeryville, CA (US);
Chung-Ming Yu, Taipei, TW;
Assignee:
Academia Sinica, Taipei, TW;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 39/00 (2006.01); A61P 25/28 (2006.01); A61P 31/20 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2803 (2013.01); A61P 25/28 (2018.01); A61P 31/20 (2018.01); A61K 2039/505 (2013.01); C07K 2317/56 (2013.01); C07K 2317/76 (2013.01); C07K 2317/77 (2013.01);
Abstract
Provided herein is a method for treating neurodegenerative diseases, such as Alzheimer's disease (AD), by use of monoclonal antibody, which exhibits a binding affinity to Siglec-3 receptor. According to some embodiments of the present disclosure, the monoclonal antibody is capable of enhancing phagocytosis of neurotoxic peptides by immune cells thereby providing a neuroprotective effect to a subject in need thereof.