The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 15, 2024
Filed:
May. 09, 2019
Applicant:
Aprinoia Therapeutics Inc., Taipei, CN;
Inventors:
Ming-Kuei Jang, Taipei, CN;
Paul Tempest, Taipei, CN;
Assignee:
APRINOIA THERAPEUTICS INC., Taipei, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); A61K 49/00 (2006.01); A61K 51/04 (2006.01); C07D 401/10 (2006.01); C07D 413/10 (2006.01); C07D 417/10 (2006.01); C07D 417/14 (2006.01); C07D 495/04 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 49/0021 (2013.01); A61K 51/0455 (2013.01); C07D 401/10 (2013.01); C07D 413/10 (2013.01); C07D 417/10 (2013.01); C07D 417/14 (2013.01); C07D 495/04 (2013.01); G01N 33/6896 (2013.01); G01N 2800/2821 (2013.01);
Abstract
Described herein are compounds of formula (I), and pharmaceutically acceptable salts, solvates, hydrates, isotopically labeled derivatives and radiolabeled derivative thereof, and pharmaceutical compositions thereof. Also provided are methods and kits involving the inventive compounds or compositions for detecting and imaging Tau aggregates in the brain for detection of Alzheimer's disease (AD) in a subject.