The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 15, 2024
Filed:
Jan. 13, 2017
Genmab A/s, Valby, DK;
Lene Schantz Harlow, Frederiksberg, DK;
Timothy Warren Paul, Bloomington, IN (US);
Brendan M. Mayhugh, Bloomington, IN (US);
Kelly Ann Roby, Bloomington, IN (US);
Gregory Allan Sacha, Bargersville, IN (US);
Xiaona Jing, Riehen, CH;
Andrew Hagarman, Durham, NC (US);
Cale Halbleib, Apex, NC (US);
GENMAB A/S, Valby, DK;
Abstract
Disclosed herein are surfactant free antibody and antibody-drug-conjugate (ADC) formulations for anti-AXL antibodies and ADCs, including aqueous formulations, lyophilized formulations, and reconstituted formulations, as well as related processes and uses. The formulations are particularly suitable for an anti-AXL ADC based on an auristatin or DM1 derivative or other similarly hydrophobic drugs. Some formulations comprise histidine and mannitol.