The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 15, 2024
Filed:
Nov. 17, 2023
Applicant:
Trustees of Boston University, Boston, MA (US);
Inventors:
Joshua Edward McGee, Watertown, MA (US);
Jack Rainier Kirsch, Cambridge, MA (US);
Eric Bressler, Boston, MA (US);
Mark W. Grinstaff, Brookline, MA (US);
Wilson Wong, Brookline, MA (US);
Lidya Yidnekachew Sertse, Boston, MA (US);
Kexin Li, Boston, MA (US);
Assignee:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/02 (2006.01); A61K 39/12 (2006.01); A61K 39/155 (2006.01); A61K 39/215 (2006.01); A61P 31/04 (2006.01); A61P 37/04 (2006.01); C07K 14/005 (2006.01); C07K 14/575 (2006.01); C07K 16/28 (2006.01); C07K 16/32 (2006.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
A61K 39/215 (2013.01); A61K 39/4631 (2023.05); A61P 37/04 (2018.01); C07K 14/005 (2013.01); C07K 14/575 (2013.01); C07K 16/2803 (2013.01); C07K 16/32 (2013.01); C12N 15/86 (2013.01); A61K 2039/53 (2013.01); A61K 2239/23 (2023.05); C12N 2770/20022 (2013.01); C12N 2770/36143 (2013.01); C12N 2830/002 (2013.01); C12N 2830/50 (2013.01); C12N 2840/203 (2013.01);
Abstract
The technology described herein is directed to compositions and methods for modifying and controlling the activity of cells by expression of proteins from self-amplifying RNA (saRNA). Also described herein are compositions and methods for modifying and controlling the activity of cells by expression of proteins from self-amplifying RNA that is substituted with chemically modified nucleotides.