The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 15, 2024

Filed:

Jun. 30, 2021
Applicant:

Incube Labs, Llc, San Jose, CA (US);

Inventor:

Mir Imran, Los Altos Hills, CA (US);

Assignee:

InCube Labs, LLC, San Jose, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/38 (2015.01); A61K 35/28 (2015.01); C12N 5/071 (2010.01);
U.S. Cl.
CPC ...
A61K 35/38 (2013.01); A61K 35/28 (2013.01); C12N 5/0679 (2013.01); C12N 2502/025 (2013.01); C12N 2502/03 (2013.01); C12N 2502/1352 (2013.01); C12N 2502/1358 (2013.01); C12N 2502/23 (2013.01); C12N 2506/1346 (2013.01); C12N 2506/45 (2013.01);
Abstract

Various embodiments of the invention provide methods of treating diabetes and other glucose regulation disorders. In one embodiment, the method comprises removing L-cells from a donor, obtaining stem cells from a patient, and culturing the L-cells in the presence of the stem cells under conditions such that the stem cells differentiate into stem cell-derived L-cells (SCDLC). An amount of the SCDLC is introduced into the patient sufficient to cause a lowering of the patient's blood glucose level after ingestion of food. In another embodiment, the method comprises removing K-cells from a donor, obtaining stem cells from a patient, and culturing the K-cells in the presence of the stem cells under conditions such that the stem cells differentiate into stem cell-derived K-cells (SCDKC). An amount of the SCDKC is introduced into the patient sufficient to cause a lowering of the patient's blood glucose level after ingestion of food.


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