The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 15, 2024

Filed:

Mar. 08, 2021
Applicant:

Indiana University Research and Technology Corporation, Indianapolis, IN (US);

Inventors:

Jian-Ting Zhang, Carmel, IN (US);

Jing-Yuan Liu, Indianapolis, IN (US);

Mingji Dai, West Lafayette, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4985 (2006.01); A61K 31/498 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4985 (2013.01); A61K 31/498 (2013.01); A61P 35/00 (2018.01);
Abstract

Methods for treating various cancers by administering one or more compounds that target the dimeric protein survivin are disclosed. Pharmaceutical compositions containing such compounds are also disclosed, along with general methods of identifying anti-cancer compounds that target oncogenic dimeric proteins. Exemplary compounds that can be used in the disclosed methods of treatment and pharmaceutical compositions have the chemical structures disclosed in the specification.


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