The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 15, 2024

Filed:

Sep. 09, 2022
Applicants:

Boehringer Ingelheim International Gmbh, Ingelheim Am Rhein, DE;

Arena Pharmaceuticals, Inc., New York, NY (US);

Inventors:

Kai Gerlach, Mlttelbiberach, DE;

Daniela Gavina Berta, Milan, IT;

Marco Ferrara, San Donato Milanese, IT;

Kirsten Gutsche, Laupheim, DE;

Ursula Mueller-Vieira, Biberach an der Riß, DE;

Scott Hobson, Mittelbiberach, DE;

Frank Runge, Biberach an der Riß, DE;

Graeme Semple, San Diego, CA (US);

Viktor Vintonyak, Warthausen, DE;

Yifeng Xiong, San Diego, CA (US);

Assignees:

Boehringer Ingelheim International GmbH, Ingelheim Am Rhein, DE;

Arena Pharmaceuticals, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/497 (2006.01); A61K 31/433 (2006.01); A61K 45/06 (2006.01); C07D 403/14 (2006.01); C07D 417/14 (2006.01); C07D 487/08 (2006.01);
U.S. Cl.
CPC ...
A61K 31/497 (2013.01); A61K 31/433 (2013.01); A61K 45/06 (2013.01); C07D 403/14 (2013.01); C07D 417/14 (2013.01); C07D 487/08 (2013.01); C07B 2200/05 (2013.01); C07B 2200/09 (2013.01);
Abstract

The invention relates to 3-phenoxyazetidin-1-yl-heteroaryl pyrrolidine derivatives of general formula (I) which are agonists of GPR52, useful in treating central nervous system diseases and other diseases. In addition, the invention relates to the 3-phenoxyazetidin-1-yl-heteroaryl pyrrolidine derivatives of general formula (I) for use as a medicament, pharmaceutical compositions comprising at least a compound of general formula (I) and processes for preparing pharmaceutical compositions as well as processes for manufacture the compounds according to the invention.


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