The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 15, 2024

Filed:

Mar. 07, 2019
Applicant:

Hefei Institutes of Physical Science, Chinese Academy of Sciences, Anhui, CN;

Inventors:

Qing Song Liu, Anhui, CN;

Jing Liu, Anhui, CN;

Xi Xiang Li, Anhui, CN;

Ao Li Wang, Anhui, CN;

Zi Ping Qi, Anhui, CN;

Qing Wang Liu, Anhui, CN;

Zong Ru Jiang, Anhui, CN;

Feng Ming Zou, Anhui, CN;

Wen Chao Wang, Anhui, CN;

Chen Hu, Anhui, CN;

Cheng Chen, Anhui, CN;

Li Wang, Anhui, CN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4439 (2006.01); A61K 31/4365 (2006.01); A61K 31/497 (2006.01); A61K 31/536 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4439 (2013.01); A61K 31/4365 (2013.01); A61K 31/497 (2013.01); A61K 31/536 (2013.01); A61P 35/00 (2018.01);
Abstract

The present invention provides a novel pan-RAF kinase inhibitor, comprising a compound of formula (I) or a pharmaceutically acceptable salt, solvate, ester, acid, metabolite or prodrug thereof. The present invention also provides a use or method of the compound of formula (I) in the treatment or prevention of a disorder related to the activity of RAF and/or RAS kinase.


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