The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 08, 2024
Filed:
May. 11, 2021
Illumina, Inc., San Diego, CA (US);
Illumina Singapore Pte. Ltd., Singapore, SG;
National University of Singapore, Singapore, SG;
Saurabh Rajendra Nirantar, Singapore, SG;
Jasmine Puay Suan Chua, Singapore, SG;
Sergio Peisajovich, San Diego, CA (US);
Wen Shan Yew, Singapore, SG;
Maybelle Darlene Kho Go, Singapore, SG;
Illumina, Inc., San Diego, CA (US);
Illumina Singapore Pte. Ltd., Singapore, SG;
National University of Singapore, Singapore, SG;
Abstract
Disclosed herein include recombinant terminal deoxynucleotidyl transferases (TdTs). In some embodiments, the recombinant TdT comprises an amino acid sequence that is at least 80% identical to a bovine TdT, wherein the recombinant TdT comprises one or more amino acid substitution mutations at one or more positions functionally equivalent to Glu191, Lys193, Glu194, Asp242, Lys287, Phe296, Met299, Thr342, and His421 in the bovine TdT.