The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 08, 2024
Filed:
Jan. 31, 2019
Applicant:
The Wistar Institute of Anatomy and Biology, Philadelphia, PA (US);
Inventors:
David Weiner, Merion, PA (US);
Makan Khoshnejad, Philadelphia, PA (US);
Kar Muthumani, Cherry Hill, NJ (US);
Ami Patel, Philadelphia, PA (US);
Assignee:
THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY, Philadelphia, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/40 (2006.01); A61P 3/06 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/40 (2013.01); A61P 3/06 (2018.01); A61K 2039/505 (2013.01);
Abstract
Disclosed herein is a composition including a recombinant nucleic acid sequence that encodes an antibody or fragment thereof that targets PCSK9. The disclosure also provides a method of preventing and/or treating disease, such as cardiovascular disease or hypercholesterolemia, in a subject using the composition of the invention.