The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 08, 2024

Filed:

Jul. 21, 2023
Applicant:

Flagship Pioneering Innovations Vi, Llc, Cambridge, MA (US);

Inventors:

Antonios O. Aliprantis, Natick, MA (US);

Zachary Kohl Costello, Cambridge, MA (US);

Anthony John Coyle, Boston, MA (US);

Kristen Park Hopson, Lincoln, MA (US);

Ryan Terrell Phennicie, Andover, MA (US);

Alexis Hiram Ramos, Wilbraham, MA (US);

Adam Reid Root, Newbury, MA (US);

Lana Dinic, Newton, MA (US);

Karin Alma Frieda Reif, San Francisco, CA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/24 (2006.01); A61P 11/06 (2006.01);
U.S. Cl.
CPC ...
C07K 16/244 (2013.01); A61P 11/06 (2018.01); C07K 2317/24 (2013.01); C07K 2317/565 (2013.01);
Abstract

The disclosure provides, in various embodiments, polypeptides (e.g., antibodies and antigen binding fragments thereof) that specifically bind to a thymic stromal lymphopoietin (TSLP) (e.g., a full-length human TSLP). The disclosure also provides, in various embodiments, fusion proteins comprising one or more of the polypeptides, polynucleotides encoding the polypeptides, vectors and host cells suitable for expressing the polypeptides, and methods for treating a TSLP-associated disease or condition.


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