The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 08, 2024

Filed:

Jul. 01, 2021
Applicant:

Inventisbio Co., Ltd., Shanghai, CN;

Inventors:

Xing Dai, Short Hills, NJ (US);

Yaolin Wang, Shanghai, CN;

Yueheng Jiang, Shanghai, CN;

Yanqin Liu, Shanghai, CN;

Zhe Shi, Shanghai, CN;

Zhenwu Wang, Shanghai, CN;

Liangshan Tao, Shanghai, CN;

Zixing Han, Shanghai, CN;

Haotao Niu, Shanghai, CN;

Jifang Weng, Shanghai, CN;

Assignee:

InventisBio Co., Ltd., Shanghai, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); A61K 31/282 (2006.01); A61K 31/438 (2006.01); A61K 31/519 (2006.01); A61K 33/243 (2019.01); A61P 35/00 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/282 (2013.01); A61K 31/438 (2013.01); A61K 31/519 (2013.01); A61K 33/243 (2019.01); A61P 35/00 (2018.01); C07D 519/00 (2013.01);
Abstract

Provided herein are novel compounds, for example, compounds having a Formula (I) or Formula (II), or a pharmaceutically acceptable salt thereof. Also provided herein are methods of preparing the compounds and methods of using the compounds, for example, in inhibiting KRAS G12C in a cell, and/or in treating various cancer such as pancreatic cancer, endometrial cancer, colorectal cancer, or lung cancer (e.g., non-small cell lung cancer).


Find Patent Forward Citations

Loading…