The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 08, 2024

Filed:

Dec. 28, 2021
Applicant:

National Cheng Kung University, Tainan, TW;

Inventors:

Ping-Ching Wu, Tainan, TW;

Cheng-Hsin Chuang, Tainan, TW;

Po-Heng Chen, Taoyuan, TW;

Yu-Yi Chiang, Taichung, TW;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/70 (2006.01); A61K 9/16 (2006.01); A61K 31/573 (2006.01); A61K 35/15 (2015.01); A61K 35/33 (2015.01); A61K 47/32 (2006.01); A61K 47/34 (2017.01); A61L 15/26 (2006.01); A61L 15/44 (2006.01); A61L 27/38 (2006.01); A61L 27/56 (2006.01); C08L 29/04 (2006.01); C08L 67/04 (2006.01); D01D 5/00 (2006.01); D01F 1/10 (2006.01); A61P 17/02 (2006.01);
U.S. Cl.
CPC ...
A61K 9/70 (2013.01); A61K 31/573 (2013.01); A61K 35/15 (2013.01); A61K 35/33 (2013.01); A61K 47/32 (2013.01); A61K 47/34 (2013.01); A61L 15/26 (2013.01); A61L 15/44 (2013.01); C08L 29/04 (2013.01); C08L 67/04 (2013.01); D01D 5/0015 (2013.01); D01F 1/10 (2013.01); A61P 17/02 (2018.01); C08L 2203/02 (2013.01); C08L 2203/12 (2013.01);
Abstract

Disclosed herein are electrospun fibrous matrix and its production method. The method mainly includes the steps of, mixing a first polymer and a drug to form a first mixture, and sonicating the first mixture until a plurality of microparticles are formed with the drug encapsulated therein; and mixing the plurality of microparticles with a second polymer to form a second mixture, subjecting the second mixture to a wet electrospinning process to form the electrospun fibrous matrix. The thus-produced electrospun fibrous matrix is characterized by having a plurality of first and second fibrils woven together, in which each second fibril has a plurality of drug-encapsulated microparticles independently integrated and disposed along the longitudinal direction of the second fibril. Also disclosed herein is a method for treating a wound of a subject. The method includes applying the present electrospun fibrous matrix to the wound of the subject.


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