The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 08, 2024
Filed:
Feb. 28, 2023
Applicant:
Loyola University of Chicago, Chicago, IL (US);
Inventors:
Daniel Paul Becker, Glenview, IL (US);
Marlon Ray Lutz, Jr., Grayslake, IL (US);
Assignee:
LOYOLA UNIVERSITY OF CHICAGO, Chicago, IL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 41/00 (2020.01); A61K 47/54 (2017.01); C07F 7/08 (2006.01);
U.S. Cl.
CPC ...
A61K 41/0095 (2013.01); A61K 47/545 (2017.08); C07F 7/0814 (2013.01);
Abstract
Disclosed herein are novel carborane hydroxamic acid matrix metalloproteinase (“MMP”) inhibitors and agents bearing borane-containing moieties and methods for their use in treating or preventing a disease, such as cancer and rheumatoid arthritis. In particular, disclosed herein are compounds of Formula (I) and pharmaceutically acceptable salt thereof: Formula (I) wherein the substituents are as described.