The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 08, 2024
Filed:
Oct. 19, 2020
Applicant:
The Children's Medical Center Corporation, Boston, MA (US);
Inventors:
Carla F. Kim, Boston Charlestown, MA (US);
Sharon M. Louie, Boston, MA (US);
Erhan Ararat, Boston, MA (US);
David Raiser, Boston, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/071 (2010.01); A01K 67/0271 (2024.01); A61K 9/00 (2006.01); A61K 35/42 (2015.01); A61K 45/06 (2006.01); A61K 49/00 (2006.01); C12N 5/00 (2006.01);
U.S. Cl.
CPC ...
A61K 35/42 (2013.01); A01K 67/0271 (2013.01); A61K 9/007 (2013.01); A61K 9/0073 (2013.01); A61K 45/06 (2013.01); A61K 49/0008 (2013.01); C12N 5/0062 (2013.01); C12N 5/0688 (2013.01); C12N 5/0697 (2013.01); A01K 2207/12 (2013.01); A01K 2227/105 (2013.01); A01K 2267/0337 (2013.01); C12N 2506/02 (2013.01); C12N 2506/27 (2013.01); C12N 2506/45 (2013.01); C12N 2513/00 (2013.01);
Abstract
Various aspects described herein provide methods of generating alveolar or alveolar/airway organoids from a population of lung cells to differentiate into alveolar or alveolar/airway organoids. Also provided herein are methods and compositions for treating lung disease comprising transplantation of the alveolar or alveolar/airway organoids, or a cell isolated therefrom to a subject.