The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 08, 2024
Filed:
Dec. 14, 2021
Applicant:
Rutgers, the State University of New Jersey, New Brunswick, NJ (US);
Inventors:
Dongfang Liu, Millburn, NJ (US);
Minh Ma, New Brunswick, NJ (US);
Saiaditya Badeti, New Brunswick, NJ (US);
Assignee:
Rutgers, The State University of New Jersey, New Brunswick, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 35/17 (2015.01); A61P 31/14 (2006.01); C07K 14/54 (2006.01); C07K 14/705 (2006.01); C07K 14/715 (2006.01); C07K 14/725 (2006.01); C07K 16/10 (2006.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 35/17 (2013.01); A61P 31/14 (2018.01); C07K 14/5443 (2013.01); C07K 14/7051 (2013.01); C07K 14/70521 (2013.01); C07K 14/7151 (2013.01); C07K 16/10 (2013.01); A61K 38/00 (2013.01); A61K 39/00 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01);
Abstract
Chimeric antigen receptors (CARs) including an scFv binding to coronavirus spike protein (S309 scFv), nucleic acids encoding the CARs, vectors including nucleic acids encoding the CARs, and cells expressing the CARs are provided. Methods of treating a subject with coronavirus are also provided, including administering to the subject a modified immune cell expressing a disclosed CAR.