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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12109190 B1

PDFFull Text
Date of Patent:
Oct. 08, 2024

Filed:

Aug. 24, 2022

Urolithins as immune response enhancers

Applicant:

Amazentis SA, Lausanne, CH;

Inventors:

Anurag Singh, Crissier, CH;

Davide D'Amico, Renens, CH;

Penelope Andreux, Eclepens, CH;

William Blanco-Bose, La Croix, CH;

Christopher L. Rinsch, Morges, CH;

Assignee:

Amazentis SA, Lausanne, CH;

Attorneys:

Foley Hoag LLP

Dana M. Gordon

Lawrence P. Tardibono

Primary Examiner:

Savitha M Rao

Int. Cl.
CPC ...
A61K 31/37 (2006.01); A61K 31/335 (2006.01); A61K 39/00 (2006.01); A61K 39/145 (2006.01); A61K 39/39 (2006.01); A61P 1/04 (2006.01); A61P 1/16 (2006.01); A61P 1/18 (2006.01); A61P 13/12 (2006.01); A61P 17/00 (2006.01); A61P 19/02 (2006.01); A61P 19/08 (2006.01); A61P 21/00 (2006.01); A61P 31/16 (2006.01); A61P 35/00 (2006.01); C07D 311/80 (2006.01);
U.S. Cl.
CPC ...
A61K 31/37 (2013.01); A61K 31/335 (2013.01); A61K 39/0011 (2013.01); A61K 39/145 (2013.01); A61K 39/39 (2013.01); A61P 31/16 (2018.01); A61K 2039/55 (2013.01); A61K 2039/55511 (2013.01); A61P 1/04 (2018.01); A61P 1/16 (2018.01); A61P 1/18 (2018.01); A61P 13/12 (2018.01); A61P 17/00 (2018.01); A61P 19/02 (2018.01); A61P 19/08 (2018.01); A61P 21/00 (2018.01); A61P 35/00 (2018.01); C07D 311/80 (2013.01);
Abstract

Disclosed are compounds for use in raising an immune response to an antigen and/or enhancing, modulating or augmenting an immune response to an antigen. Particularly the use of urolithins. The invention also relates to immune enhancers comprising urolithins, methods of using such immune enhancers and processes for the preparation of such immune enhancers. The invention also relates to the use of urolithins in methods for modulating stem cell function, for example, enhancing stem cell numbers, promoting stem cell regeneration and promoting stem cell differentiation.

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