The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 08, 2024
Filed:
Mar. 27, 2020
Essa Pharma Inc., Vancouver, CA;
The University of British Columbia, Vancouver, CA;
Provincial Health Services Authority, Vancouver, CA;
Peter Virsik, Portola Valley, CA (US);
Han-Jie Zhou, Foster City, CA (US);
Marianne Dorothy Sadar, West Vancouver, CA;
Raymond John Andersen, Vancouver, CA;
Kunzhong Jian, Surrey, CA;
Daniel Andrew Golec, Vancouver, CA;
ESSA PHARMA INC., Vancouver, CA;
THE UNIVERSITY OF BRITISH COLUMBIA, Vancouver, CA;
PROVINCIAL HEALTH SERVICES AUTHORITY, Vancouver, CA;
Abstract
The present disclosure generally relates to pharmaceutical compositions and combinations comprising an androgen receptor N-terminal domain inhibitor or an inhibitor and a second therapeutically active agent, such as an CDK4/6 inhibitor, a Pin1 inhibitor (inhibitor of peptidyl-prolyl cis/trans isomerases), or an antiandrogen. In particular, the present disclosure relates to pharmaceutical compositions and combinations useful for treatment of various cancers, for example breast cancer and prostate cancer. Further, the present disclosure relates administering an androgen receptor N-terminal domain inhibitor in combination with radiation therapy for treatment of various cancers.