The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 01, 2024
Filed:
Sep. 11, 2019
Applicant:
Rijksuniversiteit Groningen, Groningen, NL;
Inventors:
Gang Huang, Beijing, CN;
Giovanni Maglia, Glimmen, NL;
Assignee:
Rijksuniversiteit Groningen, Groningen, NL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/487 (2006.01); C07K 14/435 (2006.01); G01N 27/447 (2006.01);
U.S. Cl.
CPC ...
G01N 33/48721 (2013.01); C07K 14/43595 (2013.01); G01N 27/44791 (2013.01); C07K 2319/03 (2013.01); C07K 2319/21 (2013.01); C07K 2319/22 (2013.01);
Abstract
The invention relates to the field of nanopores, in particular to engineered Fragaceatoxin C (FraC) nanopores and their application in analyzing biopolymers and other (biological) compounds, such as single-molecule (protein) sequencing. Provided is a system comprising oligomeric FraC nanopores comprised in a lipid bilayer, wherein the sum of the nanopore fraction in the heptameric (Type II) state and the nanopore fraction in the hexameric (Type III) state represents at least 60% of the total number of FraC nanopores.