The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 01, 2024

Filed:

Aug. 10, 2021
Applicant:

Integrated Dna Technologies, Inc., Coralville, IA (US);

Inventors:

Vladimir Makarov, Ann Arbor, MI (US);

Laurie Kurihara, Ann Arbor, MI (US);

Assignee:

Integrated DNA Technologies, Inc., Coralville, IA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6855 (2018.01); C12N 9/12 (2006.01); C12P 19/34 (2006.01); C12Q 1/6806 (2018.01); C12Q 1/6869 (2018.01);
U.S. Cl.
CPC ...
C12P 19/34 (2013.01); C12N 9/1241 (2013.01); C12Q 1/6806 (2013.01); C12Q 1/6855 (2013.01); C12Q 1/6869 (2013.01); C12Q 2521/131 (2013.01); C12Q 2525/121 (2013.01); C12Q 2525/173 (2013.01); C12Q 2525/186 (2013.01); C12Q 2525/191 (2013.01); C12Q 2525/204 (2013.01);
Abstract

The present invention is directed to methods and compositions for adding tails of specific lengths to a substrate polynucleotide. The invention also contemplates methods and compositions for immobilization of tailed substrates to a solid support. The disclosure contemplates that the attenuator molecule is any biomolecule that associates with a tail sequence added to a substrate polynucleotide and controls the addition of a tail sequence to the 3' end of the substrate polynucleotide. The sequence that is added to the substrate polynucleotide is referred to herein as a tail sequence, or simply a tail, and the process of adding a nucleotide to a substrate polynucleotide is referred to herein as tailing.


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