The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 01, 2024
Filed:
Dec. 23, 2020
Applicant:
Ajinomoto Co., Inc., Tokyo, JP;
Inventors:
Sergey Vasilievich Smirnov, Moscow, RU;
Irina Lvovna Tokmakova, Moscow, RU;
Assignee:
AJINOMOTO CO., INC., Tokyo, JP;
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 19/26 (2006.01); C12N 9/10 (2006.01); C12N 9/16 (2006.01); C12N 15/52 (2006.01);
U.S. Cl.
CPC ...
C12P 19/26 (2013.01); C12N 9/13 (2013.01); C12N 9/16 (2013.01); C12N 15/52 (2013.01); C12Y 208/02001 (2013.01); C12Y 208/02008 (2013.01); C12Y 301/03002 (2013.01); C12Y 301/03007 (2013.01);
Abstract
A method for enzymatic sulfurylation of a substrate is provided which includes the steps of reacting the substrate with 3'-phosphoadenosine-5′-phosphosulfate (PAPS) in a medium containing a bacterium belonging to the family Enterobacteriaceae to produce a sulfated derivative of the substrate, and collecting the sulfated derivative from the medium, wherein the bacterium has been modified to produce, at least, a protein having sulfotransferase activity, and to attenuate expression of an aphA gene, a cysQ gene, or a cpdB gene, or a combination of these.