The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 01, 2024
Filed:
Aug. 19, 2021
Applicant:
Sarepta Therapeutics, Inc., Cambridge, MA (US);
Inventor:
Colin O'Banion, Durham, NC (US);
Assignee:
Sarepta Therapeutics, Inc., Cambridge, MA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/86 (2006.01); A61K 38/18 (2006.01); A61K 48/00 (2006.01); A61P 25/28 (2006.01); C07K 14/475 (2006.01); C07K 14/61 (2006.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); A61K 38/185 (2013.01); A61K 48/0058 (2013.01); A61K 48/0066 (2013.01); A61P 25/28 (2018.01); C07K 14/475 (2013.01); C07K 14/61 (2013.01); C12N 2750/14143 (2013.01); C12N 2750/14171 (2013.01); C12N 2830/008 (2013.01); C12N 2830/15 (2013.01); C12N 2830/38 (2013.01); C12N 2830/50 (2013.01);
Abstract
The disclosure provides nucleic acids (comprising AAV expression cassettes), AAV vectors, and compositions for use in methods for treating and/or delaying the onset of diseases associated with mutations in the mecp2 gene, such as Rett Syndrome. Also, provided herein are methods for treating and/or delaying the onset of brain-derived neurotrophic factor (BDNF)-associated diseases.