The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 01, 2024

Filed:

May. 15, 2020
Applicant:

Humacyte, Inc., Durham, NC (US);

Inventors:

Robert Schutte, Cary, NC (US);

Amanda Elizabeth Basciano, Apex, NC (US);

Dustin Cashman, Chapel Hill, NC (US);

Joshua McCall, Seattle, WA (US);

Laura E. Niklason, Greenwich, CT (US);

Heather L Prichard, Wake Forest, NC (US);

Justin T. Strader, Durham, NC (US);

Assignee:

Humacyte, Inc., Durham, NC (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12M 3/00 (2006.01); C12M 1/00 (2006.01); C12M 1/34 (2006.01); C12M 1/42 (2006.01);
U.S. Cl.
CPC ...
C12M 21/08 (2013.01); C12M 23/58 (2013.01); C12M 29/12 (2013.01); C12M 29/14 (2013.01); C12M 35/04 (2013.01); C12M 41/40 (2013.01);
Abstract

Embodiments of the present disclosure are directed to apparatuses and methods for a pulsing system which can be configured to provide pressure pulses to a fluid communication tube to/from a bioreactor (for example). Such a system may comprise one or more of, and preferably a plurality of a pulsing motor, a compression plate, one or more fluid communications tubes comprising a biomedia fluid tube configured to direct biomedia fluid into and out of one or more bioreactors, and/or an intra-luminal fluid tube configured to direct intra-luminal fluid through a mandrel tube provided in each bioreactor, and one and/or another of a cam, gearing, and/or actuator configured to repetitively moving the compression plate so as to repetitively compress and release at least a portion of a respective intra-luminal fluid tube for a respective bioreactor to effect a temporary pressure increase (distension or strain) in a respective mandrel-tube according to the predetermined time period.


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