The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 01, 2024

Filed:

Apr. 09, 2019
Applicant:

Peking University, Beijing, CN;

Inventors:

Xinhua Wan, Beijing, CN;

Xichong Ye, Beijing, CN;

Bowen Li, Beijing, CN;

Jie Zhang, Beijing, CN;

Assignee:

PEKING UNIVERSITY, Beijing, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C08J 3/215 (2006.01); B03C 1/005 (2006.01); B03C 1/01 (2006.01); B03C 1/015 (2006.01); B03C 1/02 (2006.01); B03C 1/035 (2006.01); B03C 1/28 (2006.01); B82Y 30/00 (2011.01); C07B 57/00 (2006.01); C07C 227/34 (2006.01); C07C 231/20 (2006.01); C07C 231/24 (2006.01); C08F 212/08 (2006.01); C08F 220/56 (2006.01); C08F 220/58 (2006.01); C08F 293/00 (2006.01); C08J 3/24 (2006.01); C08K 3/22 (2006.01); C08K 5/09 (2006.01); C08K 9/10 (2006.01); B82Y 25/00 (2011.01); B82Y 40/00 (2011.01); C07C 237/06 (2006.01); C08F 220/60 (2006.01);
U.S. Cl.
CPC ...
C08J 3/215 (2013.01); B03C 1/005 (2013.01); B03C 1/01 (2013.01); B03C 1/015 (2013.01); B03C 1/02 (2013.01); B03C 1/035 (2013.01); B03C 1/286 (2013.01); C07B 57/00 (2013.01); C07C 227/34 (2013.01); C07C 231/20 (2013.01); C07C 231/24 (2013.01); C08F 212/08 (2013.01); C08F 220/56 (2013.01); C08F 220/58 (2013.01); C08F 293/005 (2013.01); C08J 3/245 (2013.01); C08K 3/22 (2013.01); C08K 5/09 (2013.01); C08K 9/10 (2013.01); B03C 2201/18 (2013.01); B03C 2201/26 (2013.01); B82Y 25/00 (2013.01); B82Y 30/00 (2013.01); B82Y 40/00 (2013.01); C07B 2200/07 (2013.01); C07C 237/06 (2013.01); C08F 220/603 (2020.02); C08F 2438/03 (2013.01); C08J 2325/08 (2013.01); C08K 2003/2275 (2013.01); C08K 2201/003 (2013.01); C08K 2201/01 (2013.01); C08K 2201/011 (2013.01);
Abstract

A core-shell nanocomposite is formed by co-assembly of an amphiphilic polymer and hydrophobically modified magnetic nanoparticles, with its core being a hydrophobically modified magnetic nanomaterial and its shell being the amphiphilic polymer, wherein hydrophilic segments in the amphiphilic polymer are located at an outermost layer of the shell. The above composite can be used as additives in the crystallization of conglomerates and obtain optically pure crystals of both enantiomers in a single process. The key thereof is that the composite is used to enrich molecules with the same configuration while inhibit the crystallization of the other enantiomer in a supersaturated solution of conglomerates, such that a non-magnetic crystal and a magnetic crystal (which are enantiomers of each other) are generated in a unit operation. Optically pure crystals of both enantiomers with over 90 ee % can be obtained by one-time crystallization, and the total yield can be as high as 40%.


Find Patent Forward Citations

Loading…